Drug intelligence / Profile preview

[18F]TZ4877

Development stage
Preclinical
Lead developer
Sun Yat-sen University
Modality
Antibody-Radionuclide Conjugates → Antibody Conjugates → Antibody-Based Therapeutics, Positron Emitters → Radiopharmaceuticals
01

Overview

[18F]TZ4877: sourced facts only. name: "This study aimed to use the sphingosine 1-phosphate receptor 1 (S1PR1) targeted tracer [18F]TZ4877 with PET/CT to assess synovial inflammation in a collagen-induced arthritis (CIA) mouse model." [PMID:40923515]; target: "This study aimed to use the sphingosine 1-phosphate receptor 1 (S1PR1) targeted tracer [18F]TZ4877 with PET/CT to assess synovial inflammation in a collagen-induced arthritis (CIA) mouse model." [PMID:40923515]; developer: "Department of Rheumatology, The Fifth Affiliated Hospital, Sun Yat-Sen University, Zhuhai, Guangdong 519000, China." [PMID:40923515]; modality: "The radiotracer holds promise as a noninvasive tool for the quantitative diagnosis of RA." [PMID:40923515]; stage: "In PET/CT imaging of RA, [18F]TZ4877 can be used to detect the expression of S1PR1 effectively in CIA mouse models." [PMID:40923515]

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